Health

Alert

VANCOMYCIN RESISTANT STAPHYLOCOCCUS AUREUS (VRSA) CASE CONFIRMED IN DELAWARE

Background

Delaware Division of Public Health (DPH) reports a confirmed case of vancomycin resistant Staphylococcus aureus (VRSA). The 63

year old patient with multiple co-morbidities was recently hospitalized in Delaware and was a short term resident of a Delaware long term

care facility in addition to receiving outpatient hemodialysis. On April 6, lab tests by the Centers for Disease Control and Prevention

(CDC) convirmed VRSA. The patient was later transferred to a Pennsylvania hospital.

The VRSA isolated by the DPH Laboratory and CDC is susceptible to daptomycin, linezolid, tigecycline, doxycycline, tetracycline and

bactrium.

Staphylococcus aureus is an important cause of healthcare and community-associated infections. Diseases associated with this

common pathogen range from mild skin and soft tissue infections to potentially fatal systemic infections and affects individuals of all

ages. Previously uniformly susceptible to penicillin, widespread use of this antibiotic led to increased resistance and resultant

reliance on vancomycin for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections. The increased use of

vancomycin has resulted in a change of the susceptibility of Staphylococcus aureus to this antibiotic.

The possibility of VRSA should be considered in patients who present with skin infections, bloodstream infections, surgical wound

infections, and have history of underlying chronic conditions (such as chronic skin ulcers and diabetes), previous treatment with

vancomycin, and history of MRSA or vancomycin resistant enterococcus (VRE).

VRSA infections are rare in the United States (U.S.). This Delaware case represents only the 11^th confirmed case of VRSA

reported in the U.S. DPH Bureau of Epidemiology is investigating this case and possible contacts per CDC recommendation.

Transmission of VRSA

VRSA is potentially transmissible from person-to-person, but such transmission has not been documented. To date, all patients with

confirmed VRSA infections have had significant co-morbidities such as diabetes and renal disease, previous infections with MRSA, invasive

procedures and devices, recent hospitalizations and recent exposure to vancomycin and other antimicrobial agents.

Prevention and Control

Infection control guidelines and practices in healthcare facilities are well documented and include the prevention and control of

multidrug-resistant organisms (MDRO), including VRSA. Stringent handwashing, the use of barrier and contact precautions and appropriate

antibiotic use are the basis for controlling the spread of any infectious disease.

For detailed CDC guidelines for the control of VRSA please reference:

http://www.cdc.gov/ncidod/dhqp/pdf/ar/visa_vrsa_guide.pdf

For More Information

For more information on VRSA, please visit the CDC website at: http://www.cdc.gov/ncidod/dhqp/ar_visavrsa.html.

DPH, Bureau of Epidemiology can be contacted at (302) 744-1033 or 1-888-295-5156.

************************************

You are receiving this email because you are a registered member of the Delaware Health Alert Network. If you are not a member and would

like to subscribe, please register at https://healthalertde.org

Please note: Some of the files available on this page are in Adobe PDF format which requires Adobe Acrobat Reader. A free copy of Adobe Acrobat Reader can be downloaded directly from Adobe . If you are using an assistive technology unable to read Adobe PDF, please either view the corresponding text only version (if available) or visit Adobe’s Accessibility Tools page.