Health

Alert

THIRD VANCOMYCIN RESISTANT STAPHYLOCOCCUS AUREUS (VRSA) CASE IDENTIFIED IN DELAWARE

The Delaware Division of Public Health (DPH) has identified a case of vancomycin resistant Staphylococcus aureus (VRSA). The 70-year-old

patient with multiple co-morbidities is a resident of New Castle County, Delaware.

The VRSA was isolated by a commercial laboratory and confirmed by the Centers for Disease Control and Prevention (CDC) on Friday, June

29, 2012 and the Delaware Public Health Laboratory on Saturday, June 30, 2012.

Staphylococcus aureus is an important cause of healthcare and community-associated infections. Diseases associated with this common

pathogen range from mild skin and soft tissue infections to potentially fatal systemic infections and affects individuals of all ages.

Previously uniformly susceptible to penicillin, widespread use of this antibiotic led to increased resistance and resultant reliance on

vancomycin for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections. The increased use of vancomycin has resulted

in a change of the susceptibility of Staphylococcus aureus to this antibiotic.

The possibility of VRSA should be considered in patients who present with skin infections, bloodstream infections, surgical wound

infections, and have history of underlying chronic conditions (such as chronic skin ulcers and diabetes), previous treatment with

vancomycin, and history of MRSA or vancomycin resistant enterococcus (VRE).

This Delaware case represents only the 13th confirmed case of VRSA reported in the U.S.  DPH confirmed two additional cases of VRSA

in early April and September 2010. The DPH Bureau of Epidemiology is investigating this case and possible contacts per CDC

recommendation.

Transmission of VRSA

VRSA is potentially transmissible from person-to-person, but such transmission has not been documented. To date, all patients with

confirmed VRSA infections have had significant co-morbidities such as diabetes and renal disease, previous infections with MRSA, invasive

procedures and devices, recent hospitalizations and recent exposure to vancomycin and other antimicrobial agents.

Prevention and Control

Infection control guidelines and practices in healthcare facilities are well documented and include the prevention and control of

multidrug-resistant organisms including VRSA. Stringent handwashing, the use of barrier and contact precautions and appropriate

antibiotic use are the basis for controlling the spread of any infectious disease.

For detailed CDC guidelines for the control of VRSA please reference:

http://www.cdc.gov/HAI/organisms/visa_vrsa/visa_vrsa.html

DPH, Bureau of Epidemiology can be contacted at (302) 744-1033 or 1-888-295-5156.

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